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启明星 | 信念医药与AskBio达成国际合作,通过世界水平的创新基因疗法解决全球患者未被满足的医疗需求 | Bilingual

基因疗法 AskBio


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日前,启明创投投资企业、全球领先的专注于前沿基因治疗领域的高科技企业信念医药集团(Belief BioMed Inc.)(下称“信念医药”)宣布,与拜耳集团的全资独立运营的基因疗法子公司Asklepios BioPharmaceutical, Inc.(下称“AskBio”)达成战略合作,共同探索创新基因疗法潜力。


根据合同条款,双方将结合各自在基因治疗技术方面的专业积淀和优势力量,深入研究和探索通过肝脏靶向治疗途径实现创新基因治疗方案的疾病领域,以满足全球患者未被满足的医疗需求。

信念医药联合创始人、董事长兼首席科学家肖啸博士表示:“信念医药聚焦深耕基因治疗领域,自成立以来在研发、临床、生产等方面均取得瞩目成果,公司自主研发的重组腺相关病毒(rAAV)载体递送系统获得行业广泛认可,相关研究成果发表于国际权威期刊。两家全球化的创新药企信念医药与AskBio达成此次战略合作,主要基于真诚互信、志同道合,以及双方的独特优势和互补资源,以此聚力将更多创新治疗方案早日带给全球患者。”

AskBio是一家全球总部位于美国北卡罗来纳州的公司,专注开发护航生命健康、提升生活质量的基因治疗药物。其产品管线非常丰富,覆盖神经肌肉、中枢神经系统、心血管和代谢等多个疾病领域。该公司已经自主研发数百种用于基因治疗药物的衣壳和启动子,其中几种已进入临床前和临床试验阶段。

信念医药是全球领先的集基因治疗产品研发、生产和临床应用为一体的高科技企业,广泛覆盖血友病、杜氏肌营养不良症、帕金森病、骨关节炎等多种疾病领域的治疗。公司在推进基因治疗方面的努力得到了国际认可,其药物已获得美国食品药品监督管理局的孤儿药认定。本次合作将进一步强化公司在基因治疗领域的核心竞争力,为全球患者带来更多创新性基因疗法,打下更为牢固的基础。

AskBio首席执行官Gustavo Pesquin先生表示:“与信念医药的战略合作是我们在AskBio如何工作的一个很好诠释。肖啸博士于信念医药以及此前担任AskBio联合创始人期间,在基因治疗领域做出了卓越贡献,亦使得此次合作尤为特别。信念医药是一家全球化的创新型企业,我们拥有共同的志向和目标,通过领域内资源整合和优势互补,可以为我们的管线资产找到最佳的前行路径, 更高效地开发出针对重大未被满足需求的全新疗法。”

信念医药联合创始人兼首席执行官郑静博士表示:“信念医药近些年的高质量稳步发展,有赖于信念人的专业专注和不懈努力,更离不开行业各界的精诚合作和有力支持。公司始终积极构建开放、协作、共赢的伙伴关系,一如这次两家企业的合作,便是一种创新且递进的合作模式,期待合力之下填补更多未被满足的临床需求,同时,信念医药向服务全球病患的目标再次迈出坚实一步。”



Belief BioMed and AskBio, Subsidiary of Bayer, Announced Global Collaboration to Address Unmet Medical Needs with World-Class Gene Therapies


Belief BioMed Inc. (BBM), a global leading biotech company focusing on innovative gene therapies, announced a new strategic collaboration with Asklepios BioPharmaceutical, Inc. (AskBio), a gene therapy company wholly owned and independently operated as a subsidiary of Bayer AG, to explore the potential for new gene therapies. 

 

Under the terms of the contract, the companies will combine efforts and experience in gene therapy technology to explore potential therapies in diseases that may be treatable using a liver-targeted approach, addressing unmet medical needs across diverse patient populations around the world.

 

Dr. Xiao Xiao, Co-founder, Chairman and CSO of BBM, said, "Focusing on gene therapy, BBM has achieved exciting results in research, development and production since its inception. The company's proprietary recombinant adeno-associated virus (rAAV) vector system has also been widely recognized by the industry, with key findings published in prestigious scientific journals. Our strategic partnership with AskBio is based on our shared vision, mutual trust and complementary resources and strength. With our joint effort we will be able to bring more innovative treatments in a timely manner to patients around the globe."

 

With global headquarters in North Carolina, US, AskBio is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular, central nervous system, cardiovascular, and metabolic disease indications. The company has generated hundreds of proprietary capsids and promoters, several of which have entered pre-clinical and clinical testing.

 

BBM is a global leading biotech company that integrates the R&D, manufacturing, and clinical application of gene therapy products. Its pipeline covers a wide range of therapeutic areas that include hemophilia, Duchenne Muscular Dystrophy (DMD), Parkinson's disease, and osteoarthritis. The company's efforts to advance gene therapy have gained international recognition, with the US FDA granting Orphan Drug Designation, underscoring the high potential impact of its therapies. This collaboration will further strengthen the company's core competitiveness in gene therapy and create a solid foundation for bringing additional new innovative gene therapies to patients worldwide.

 

Gustavo Pesquin, CEO of AskBio, said, "This strategic collaboration with BBM is an excellent example of how we work at AskBio and is particularly special given the extraordinary contributions Dr. Xiao Xiao has made to the field while at BBM and before as a co-founder of AskBio. Collaborating with innovative, like-minded global partners with complementary gene therapy expertise enables us to find the best way forward for our pipeline assets and bolster our efforts to advance new therapies for conditions with significant unmet need."

 

Dr. Jane Zheng, Co-founder and CEO of BBM, said, "The high-quality, steady development of BBM in recent years is not only attributable to the dedication and unremitting efforts of our employees, but also to the strong support given by our external partners. BBM has always been actively building open, collaborative, and win-win partnerships, just like the cooperation between the two companies this time. Under the framework of this novel and progressive collaboration, we look forward to working together with AskBio to address a wider range of unmet medical needs and advance BBM's goal of being a key contributor to the gene therapy landscape, serving patients worldwide."


往 期 回 顾


启明星 | 信念医药与武田中国宣布在华达成B型血友病领域独家商业化合作
启明荣誉 | 启明创投梁颕宇及3位投资企业创始人获评36氪SHE POWER·影响力女性
启明观点 | 启明创投梁颕宇:持续加大对关键领域的支持力度,推动产业链和价值链向更高端迈进

启明创投成立于2006年。目前,启明创投旗下管理11只美元基金,7只人民币基金,已募管理资产总额达到95亿美元。自成立至今,专注于投资科技及消费(Technology and Consumer, T&C)、医疗健康(Healthcare)等行业早期和成长期的优秀企业。

截至目前,启明创投已投资超过530家高速成长的创新企业,其中有超过200家分别在美国纽交所、纳斯达克,香港交易所,上交所及深交所等交易所上市,或通过并购等方式退出,有70多家企业成为行业公认的独角兽或超级独角兽企业。

启明创投投资企业中,很多已经成长为各自领域中最具影响力的公司,包括小米集团(01810.HK)、美团(03690.HK)、哔哩哔哩(NASDAQ:BILI, 09626.HK)、知乎(NYSE:ZH, 02390.HK)、石头科技(688169.SH)、甘李药业(603087.SH)、泰格医药(300347.SZ, 03347.HK)、再鼎医药(NASDAQ:ZLAB, 09688.HK)、康希诺生物(688185.SH, 06185.HK)、Schrödinger(NASDAQ:SDGR)、惠泰医疗(688617.SH)、诺辉健康(06606.HK)、三友医疗(688085.SH)、艾德生物(300685.SZ)、贝瑞基因(000710.SZ)、神州细胞(688520.SH)、优必选(09880.HK)、圆心科技、康缔亚、信念医药、文远知行、壁仞科技等。


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