ChiCTR-IOR-15007465
正在进行
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2015-11-25
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愛滋病病毒感染者
以基因亞型指導低劑量依法韋侖在華裔愛滋病病毒感染者的臨床應用
以基因亞型指導低劑量依法韋侖在華裔愛滋病病毒感染者的臨床應用
以基因亞型指導低劑量依法韋侖在華裔愛滋病病毒感染者的臨床應用
随机交叉对照
Ⅳ期
simple randomization
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The Chinese University of Hong Kong
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50
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1990-01-01
1990-01-01
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1) HIV-infected adults older than 18 years old; 2) Stable CD4 T-cell counts (over 200 cells per uL) and undetectable viral load (plasma HIV-1 RNA < 75 copies per mL); 3) on HAART containing standard dose EFV and 2 nucleoside/nucleotide reverse transcriptase inhibitors (e.g. tenofovir and emtricitabine).；
登录查看1) pregnant or nursing mothers; 2) have concurrent opportunistic infection or malignant disease, or any AIDS-defining illness; 3) on treatment or prophylaxis for an opportunistic infection; 4) have inadequate renal function (estimated creatinine clearance of <50 mL/min) or significantly deranged laboratory tests (e.g. ALT 1.5*upper limit of normal); 5) have documented non-adherence to study medications or HAART or documented history of illicit substance abuse; 6) illiterate or unable to communicate with study team; or 7) unable or refuse to participate or give consent.；
登录查看School of Pharmacy, Chinese University of Hong Kong
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