ChiCTR2100050197
尚未开始
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2021-08-22
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SUBSTANCE USE DISORDER WITH ANY TYPE OF PSYCHIATRIC DISORDERS
The effectiveness of MICM to improve medication adherence for dual-diagnosed patients
A pilot randomized controlled trial of integrative Motivational Interviewing and Contingency Management program (MICM) for dual-diagnosed patients to enhance psychiatric medication adherence
The proposed project will adopt a single-blinded, multi-centre pilot randomized controlled trial (RCT) design to determine the feasibility and preliminary effectiveness of a multi-model, integrative Motivational Interviewing and Contingency Management program (MICM), in comparison with the usual care (i.e., case management), at immediately after intervention and 3-months post-intervention. The following outcomes will be assessed: 1. medication adherence (primary outcome); and 2. psychiatric symptoms, frequency of substance abuse and psychiatric hospitalizations (secondary outcomes). Moreover, the perceived usefulness and areas of improvement of the MICM program will be evaluated to make necessary improvement in the future clinical application.
随机抽样
Ⅰ期
Block randomization with block size of 6-8 will be used to maintain a balanced number of participants in both groups (Efird, 2011). A sequence of group identifiers (I or C) based on computer-generated random codes is prepared in advance and put in serially numbered sealed opaque envelopes by a clerical&
The researcher who is also the intervention deliverer will not know which participant will be assigned to which group before opening of opaque envelope. After allocation has been done, both participants and researcher cannot be blinded.
SELF
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43
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2021-08-23
2022-12-31
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1. Adults, aged 18-64 years Hong Kong residents; 2. Diagnosed with substance-use disorder and comorbid with at least one type of other mental disorder in the Diagnostic and Statistical Manual – fourth version (text revised) (DSM-IV-TR) / fifth version (DSM-5), or International Classification of Diseases – 10th (ICD-10) / 11th version (ICD-11); 3. Able to give written consent as recommended by psychiatrist and read/write Chinese language; 4. Being prescribed at least one type of oral psychiatric medication.；
登录查看1. Having organic psychiatric disorder AND/OR learning disability; 2. Having been prescribed depot-only (injection) medication or no medication; 3. Having visual, language or communication difficulties.；
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精准药物2024-11-23
亚泰制药2024-11-23
昌郁医药2024-11-22
上海和誉生物医药科技有限公司2024-11-22
云顶新耀2024-11-22
金斯瑞生物2024-11-22
细胞与基因治疗领域2024-11-22
肝脏时间2024-11-22
医药笔记2024-11-22
生物安全情报网2024-11-22
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