ChiCTR2000034916
尚未开始
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2020-07-24
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盆腔器官脫垂
Genetics and genome sequencing study of pelvic organ prolapse patients
Genetics and genome sequencing study of pelvic organ prolapse patients
This study aims to study the genome-wide spectrum, frequency of genetic variants and genome-wide copy number variants in patients with pelvic organ prolapse in order to address whether genome variants, especially sequence variants (SNVs and CNVs) in genes involved in regulating connective tissue structure or hormonal response could be a key modifying factor contributing to pelvic floor disorders and other urogynaecological conditions. In addition, a DNA bank of patients with and without POP will be established.
析因分组（即根据危险因素或暴露因素分组）
其它
N/A
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Department funding
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200;500
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2020-07-27
2025-07-31
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1. Subjects will be those planning for surgical treatment for POP, and control subjects will be those planning for hysterectomy for non-prolapse and benign gynaecological diseases; 2. Patient age 18 year old or above; 3. Willing to give written consent.；
登录查看Patient refuses to participate in the study；
登录查看N/A
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