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【ChiCTR2000030858】武汉市483例轻度新型冠状病毒肺炎(COVID-19)患者的临床特点及转归：一项来自武昌方舱医院的单中心，回顾性研究方案

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基本信息

登记号

ChiCTR2000030858

试验状态

正在进行

药物名称

药物类型

规范名称

首次公示信息日的期

2020-03-16

临床申请受理号

靶点

适应症

新型冠状病毒肺炎(COVID-19)

试验通俗题目

武汉市483例轻度新型冠状病毒肺炎(COVID-19)患者的临床特点及转归：一项来自武昌方舱医院的单中心，回顾性研究方案

试验专业题目

武汉市483例轻度冠状病毒肺炎(COVID-19)患者的临床特点及转归：一项来自武昌方舱医院的单中心，回顾性研究方案

申办单位信息

申请人联系人

申请人名称

联系人邮箱

联系人邮编

联系人通讯地址

临床试验信息

试验目的

The mobile cabin hospital played an important role in stemming China’s outbreak of COVID-19 infection, effectively isolating and treating patients with mild cases. Information about the patient's characteristics and the outcomes of mild patients' conversion to severe in mobile cabin hospitals are scarce.

试验分类

试验类型

连续入组

试验分期

其它

随机化

N/A

盲法

N/A

试验项目经费来源

自筹

试验范围

目标入组人数

483

实际入组人数

第一例入组时间

2020-02-06

试验终止时间

2020-03-15

是否属于一致性

入选标准

The mild cases were defined as those with mild clinical symptoms and no abnormalities on imaging examination; critical cases were those that met any of the following conditions: 1) respiratory failure requiring mechanical ventilation; 2) shock; 3) combined with another organ failure, the need for intensive care unit (ICU) monitoring and treatment. The process of classified management of mild and severe cases is shown in Figure 1. Among the patients we followed, 62 patients progressed to severe cases; they were transferred to designated hospitals for further treatment. Moreover, the discharge diagnostic criteria were as follows: 1) body temperature returned to normal for more than 3 d; 2) respiratory symptoms improved significantly; 3) significant improvement in lung imaging; 4) negative nucleic acid test for nasal and pharyngeal swabs twice.；

排除标准

All mild patients need to be isolated and treated in mobile cabin hospitals. After admission, patients were given antiviral and symptomatic treatment according to their condition and symptoms, and patients with fever were given antibiotics at the same time. Besides, the patient was instructed to exercise and psychological intervention, all drugs were presented in Supplementary Table S1. During the hospital stay, decide whether you need a chest CT or chest radiograph based on the patient's condition. When the patient has no fever for three days and the respiratory symptoms are relieved, start nucleic acid tests and chest radiographs or CT scans of the lungs. The decision to be discharged based on whether the test results meet discharge criteria.；

研究者信息

研究负责人姓名

试验机构

湖北省肿瘤医院

研究负责人电话

研究负责人邮箱

研究负责人邮编

430079

联系人通讯地址

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