ChiCTR-ONC-13003015
正在进行
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2013-01-22
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Atrial Fibrillation
Percutaneous Left Atrial Appendage Closure for Stroke Prevention in Atrial Fibrillation
Percutaneous Left Atrial Appendage Closure for Stroke Prevention in Atrial Fibrillation
To assess the effect and safety of Percutaneous Left Atrial Appendage Closure for Stroke Prevention in Atrial Fibrillation.
连续入组
Ⅳ期
NA
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SK Yee Funding, CUHK
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80
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2013-02-28
1990-01-01
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1. Adults above the age of 18; 2. Non-valvular AF, at high risk of stroke and who have experienced serious bleeding events or repeated nuisance bleed events whilst on warfarin or NOACs; 3. Non-valvular AF, at high risk of stroke and who are intolerant of, has significant side effect, or decline to take warfarin or NOACs; 4. Non-valvular AF, at high risk of stroke and who are poorly compliant with warfarin (Time in therapeutic range <60%) or NOACs; 5. Non-valvular AF, at high risk of stroke and who are at high risk of bleeding as evidenced by a high HAS-BLED score.；
登录查看1. Inability to take Aspirin and Clopidogrel; 2. Inability to give informed consent; 3. Patients unlikely to benefit from the therapy due to a short life expectancy; 4. NYHA 4; 5. LVEF <30%; 6. Moderate-to-severe or worse mitral or aortic valvular regurgitation or stenosis; 7. Suspected or known intracardiac thrombus; 8. Symptomatic carotid disease.；
登录查看SK Yee Funding, CUHK
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